Sayyiduna Abdullah bin Umar (may Allah be pleased with them both) says that the Messenger of Allah (peace and blessings be upon him) separated a couple because of an accusation against the wife; both of them swore oaths before the Messenger of Allah (peace and blessings be upon him), and afterwards he separated them.
Hadith Referenceالسنن الكبرى للبيهقي / كتاب اللعان / 15295