Sayyiduna Abdullah bin Umar (may Allah be pleased with them both) relates that when Sayyidah Aishah (may Allah be pleased with her) was accused, the Messenger of Allah (peace and blessings be upon him) said to Sayyiduna Usamah (may Allah be pleased with him) concerning the affair of Sayyidah Aishah: "What do you say?" He said: Subhan Allah (Glory be to Allah)! It is not permissible for us to speak of this; Glory be to You! This is a tremendous slander.
Hadith Referenceالمعجم الكبير للطبراني / مسند النساء / 19506