This excerpt is taken from Sheikh Hafiz Mubashir Hussain Lahori's book Signs of the Day of Judgment in the Light of Authentic Hadiths.
The Dajjal cannot enter Mecca and Medina
عن فاطمة بنت قيس رضي الله عنها .... وإني مخبركم عني ، إني أنا المسيح الدجال وإني يوشك أن يؤذن لي فى الخروج فأخرج فأسير فى الأرض فلا أدع قرية إلا هبطتها فى أربعين ليلة غير مكة وطيبة فهما محرمتان على كلتاهما ، كلما أردت أن أدخل واحدة منهما استقبلني ملك بيده السيف صلتا يصدني عنها وإن على كل نقب منها ملائكة يحرسونها
It is narrated from Hazrat Fatima bint Qais (RA) that: I inform you about myself, I am the Antichrist (Dajjal), and soon I will be permitted to emerge. I will come out and roam the earth, and I will trample every settlement (city) except Mecca and Medina, because these two (Mecca and Medina) are forbidden for me. Whenever I intend to enter either of these, an angel wielding a sword will come to meet me and prevent me from entering, and on every path to these two cities, there will be angels guarding them.
Reference: Muslim: Kitab al-Fitan, Bab Qissat al-Jassasah 2942; Abu Dawood 4325; Tirmidhi 253; Nasa'i 3547; Ibn Majah 2045; Humaidi 177/1; Ahmad 419/6, 420, 461, 464; Dala'il al-Nubuwwah 416/5
عن أنس بن مالك رضى الله عنه عن النبى صلى الله عليه وسلم قال : المدينة يأتيها الدجال فيجد الملائكة يحرسونها فلا يقربها الدجال قال ولا الطاعون إن شاء الله
It is narrated from Hazrat Anas bin Malik (RA) that the Prophet Muhammad (PBUH) said: When the Dajjal comes to Medina, you will find angels assigned to protect it, so neither the Dajjal can come near it nor can plague.
ان شاء الله
Reference: Bukhari: Kitab al-Fitan: Bab La Yadkhul al-Dajjal al-Madina 7134; Muslim 1387; Ahmad 493, 312/2
Hazrat Abu Huraira (RA) says that the Messenger of Allah (PBUH) said: The Dajjal will emerge from the east and head towards Medina. When he reaches near Mount Uhud, angels will turn his direction towards the land of Sham (Syria), and it is in Sham that the Dajjal will be killed.
Reference: Muslim: Kitab al-Hajj: Bab Siyanat al-Madina min Dukhul al-Ta'un wa al-Dajjal ilayha 1380; Ahmad 537/2; Tirmidhi 2234
It is narrated from Abdullah bin Shaqiq (RA) that the Messenger of Allah (PBUH), while addressing the people, said: The day of salvation, do you know which day is the day of salvation? He repeated this phrase three times, then said: The Dajjal will emerge and climb Mount Uhud and look towards Medina, then he will ask his companions (army), "Do you see this white palace? This is the mosque of Ahmad (PBUH)." Then he will come towards Medina, but on every path, he will find an angel wielding a sword. Then he will camp on marshy land near Medina. Medina will shake three times, and as a result, every hypocrite, hypocrite woman, sinner, and sinful woman will go towards the Dajjal. So this is the (Yawm al-Khalas) day of salvation.
Reference: Ahmad 455/4; Hakim: Kitab al-Fitan 474/4; Hilyat al-Awliya 214/6; Al-Mu'jam al-Kabir 230/18; Majma' al-Zawa'id 661/3; Ibn Hibban 5838; Kanz al-Ummal 248/12
Who will prove to be the toughest people for the Dajjal?
عن أبى هريرة رضى الله عنه قال : ما زلت أحب بني تميم منذ ثلاث سمعت من رسول الله صلى الله عليه وسلم يقول فيهم سمعته يقول : هم أشد أمتي على الدجال ، قال : وجاءت صدقاتهم فقال رسول الله صلى الله عليه وسلم : هذه صدقات قومنا ، وكانت سبية منهم عند عائشة فقال : أعتقيها فإنها من ولد إسماعيل
Hazrat Abu Huraira (may Allah be pleased with him) said that because of three things I heard from the Messenger of Allah (peace be upon him), I always love Banu Tamim. The Prophet (peace be upon him) said about them: that these people will be the most severe opponents of the Dajjal among my Ummah. Then (Abu Huraira, may Allah be pleased with him) said that when the Zakat money came from Banu Tamim, the Prophet (peace be upon him) said: this is the Zakat of our people. A woman from Banu Tamim was a captive (slave) with Hazrat Aisha (may Allah be pleased with her), and the Prophet (peace be upon him) said to her: free her, she is from the descendants of Hazrat Ismail (peace be upon him).
Reference: Bukhari: Book of Emancipation: Chapter on Who Owns Among the Arabs 2543 Ahmad 514/2 Muslim 2525 Sunan al-Kubra 11/7
In one narration, it is mentioned that (once) the Zakat from Banu Tamim was delayed, and a man sarcastically said that these Banu Tamim people are lazy even in sending Zakat. When the Prophet (peace be upon him) heard this, he said: Banu Tamim is my very beloved nation; always speak well of them. These people will be the ones who will attack the Dajjal with the longest spears more than anyone else.
Reference: Ahmad 230/4 Majma' al-Zawa'id 16/10 Kanz al-Ummal 61/12
The Dajjal cannot enter the Kaaba and Al-Quds:
عن سمرة بن جندب رضى الله عنه قال قال رسول الله صلى الله عليه وسلم : والله لا تقوم الساعة حتى يخرج ثلاثون كذابون آخرهم الأعور الدجال ممسوح العين اليسرى ... إنه سيظهر على الأرض كلها إلا الحرم وبيت المقدس وإنه يحصر المؤمنين فى بيت المقدس فيزلزلون زلزالا شديدا ثم يهلكه الله تبارك وتعالى وجنوده
It is narrated from Hazrat Samrah bin Jundub (RA) that the Messenger of Allah (PBUH) said: By Allah! The Day of Judgment will not occur until thirty false claimants appear, the last of whom will be the one-eyed Dajjal whose left eye will be blinded. He will take control over the entire earth but will not be able to access the Kaaba and Al-Quds. He will besiege the Muslims present in Al-Quds, and they will face severe earthquakes. Ultimately, Allah Almighty will destroy the Dajjal and his armies.
Reference: Ahmad 22/5 Majma' al-Zawa'id 448/2 Al-Mu'jam al-Kabir 227/7 Al-Isabah 26/4 Fath al-Bari 706/6