Tirmidhi

Explanation:
1:
From this hadith, it is understood that whatever substance in large quantity causes intoxication, then even a small amount of it is forbidden (haram).
This refutes the statement of those who say that wine (khamr), whether in small or large quantity, is forbidden,
but as for other intoxicating substances, only that amount is forbidden which causes intoxication, and the amount which does not cause intoxication is not forbidden.

Benefits and Issues:
In this blessed hadith, it has been explicitly stated
that every intoxicating substance, regardless of its type,
whether consumed in small or large quantity, is prohibited.
And to say or think that if it is from grapes then it is forbidden,
and if it is of another kind, then drinking it in such an amount
that does not cause intoxication is permissible,
is contrary to the command of the Messenger (sallallahu alayhi wa sallam).
Therefore, according to the leading physicians and scholars of hadith,
homeopathic, allopathic,
or Unani medicines in which alcohol,
opium,
wine, or anything else that Allah the Exalted has forbidden is present,
it is prohibited to use them for treatment.
And this is the position of the majority of scholars.
Thus, in Sahih al-Bukhari as a suspended narration and in al-Mu'jam al-Kabir as a marfu' narration, it is reported from Ibn Abbas (radi Allahu anhu):
The Messenger of Allah (sallallahu alayhi wa sallam) said: "Indeed, Allah has not placed your cure in what He has forbidden for you." (Sahih al-Bukhari, al-Ashriba, before hadith: 5614 and al-Mu'jam al-Kabir of al-Tabarani: 345/9)
Moreover, from other similar narrations and texts, it is explicitly understood
that treatment with impure and forbidden things is prohibited.
Some scholars have considered treatment with forbidden and impure things to be permissible,
and they have made an analogy with the permissibility of using carrion and blood for one in dire necessity (mudtar).
But since this analogy is contrary to the text, it is weak.
Therefore, this analogy is invalid (qiyas ma‘ al-fariq).
Because by eating carrion and blood, the necessity is removed,
and life is preserved through it,
whereas with the use of forbidden and impure things, cure is not certain,
nor is it necessary that the illness will be removed.
Rather, the Messenger of Allah (sallallahu alayhi wa sallam) has informed that this is not a cure.
Therefore, treatment with it is also not valid.

Takhrij:
«أخرجه أبوداود، الأشربة، باب ما جاء في السكر، حديث:3681، والترمذي، الأشربة، حديث:1865، وابن ماجه، الأشربة، حديث:3393، وأحمد"2 /167، 178، 3 /112، 343، والنسائي، الأشربة، حديث:5610، وابن حبان.»©Explanation:
This hadith establishes that whatever substance in large quantity causes intoxication, then even its small quantity is also prohibited to use.
The opinion of the Hanafis is that the sip which causes intoxication is indeed prohibited, but whatever amount of alcohol is consumed before that, if it does not cause intoxication, then it is permissible. However, this hadith explicitly refutes the statement of those scholars.